September 26, 2025

NFL Week 4 picks: Do Micah Parsons, Packers make Cowboys pay?

  • Micah Parsons will face the team that drafted him in 2021 for the first time Sunday.
  • Two NFC division leaders will meet in the only game featuring two 3-0 teams.
  • Who wins the league’s first regular-season game to be staged in Ireland?

Week 4 of the 2025 NFL season promises to be an eventful one.

Sunday’s lineup starts early − 9:30 a.m. ET specifically − as the Pittsburgh Steelers and Minnesota Vikings meet in the league’s first regular-season contest to be staged in Ireland. Later in the day, New York Giants rookie quarterback Jaxson Dart will make his starting debut against the AFC West-leading Los Angeles Chargers. The Philadelphia Eagles and Tampa Bay Buccaneers, division leaders themselves, will meet in the only game featuring 3-0 clubs. The Baltimore Ravens and Kansas City Chiefs will square off in a game of would-be Super Bowl hopefuls … who are both surprisingly 1-2.

But no game is likely to garner more attention than the Green Bay Packers’ highly anticipated visit to the Dallas Cowboys for ‘Sunday Night Football,’ All-Pro pass rusher Micah Parsons making his return to North Texas just a month after his shocking trade to the Pack. Could be quite a referendum for Cowboys owner Jerry Jones in front of a prime-time audience.

How does it all unfold? USA TODAY Sports’ panel of NFL experts shares its picks:

(Odds provided by BetMGM)

NFL Week 4 picks, predictions, odds

  • Seattle Seahawks at Arizona Cardinals
  • Minnesota Vikings vs. Pittsburgh Steelers
  • Los Angeles Chargers at New York Giants
  • Carolina Panthers at New England Patriots
  • Philadelphia Eagles at Tampa Bay Buccaneers
  • Washington Commanders at Atlanta Falcons
  • Cleveland Browns at Detroit Lions
  • Tennessee Titans at Houston Texans
  • New Orleans Saints at Buffalo Bills
  • Indianapolis Colts at Los Angeles Rams
  • Jacksonville Jaguars at San Francisco 49ers
  • Baltimore Ravens at Kansas City Chiefs
  • Chicago Bears at Las Vegas Raiders
  • Green Bay Packers at Dallas Cowboys
  • New York Jets at Miami Dolphins
  • Cincinnati Bengals at Denver Broncos

This post appeared first on USA TODAY